FRIDAY, Sept. 4, 2020 (HealthDay Information) — Individuals with lupus aren’t at elevated threat of hospitalization from COVID-19 attributable to steroidal medicines they take to scale back immune system exercise, a brand new examine finds.
And a associated examine discovered that individuals with inflammatory types of arthritis — comparable to rheumatoid arthritis — aren’t extra prone to be hospitalized with COVID-19 than individuals with out arthritis.
Each research had been led by researchers at NYU Grossman College of Medication, in New York Metropolis.
The findings “ought to reassure most sufferers, particularly these on immunosuppressant remedy, that they’re at no larger threat of getting to be admitted to hospital from COVID-19 than different lupus or arthritis sufferers,” Dr. Ruth Fernandez-Ruiz, co-author of the research, stated in an NYU Langone information launch.
“Individuals with lupus or inflammatory arthritis have the identical threat components for getting critically sick from COVID-19 as individuals with out these issues,” stated Fernandez-Ruiz, a postdoctoral fellow in rheumatology.
Lupus and circumstances like rheumatoid arthritis, psoriatic arthritis and spondyloarthritis are autoimmune ailments by which the immune system mistakenly assaults an individual’s personal tissues. This causes inflammation within the joints, pores and skin, kidneys and different components of the physique.
The researchers discovered that lupus sufferers taking immune-suppressing medicines — comparable to mycophenolate mofetil (CellCept) and azathioprine (Imuran) — had no larger threat of hospitalization (15 out of 24) than lupus sufferers not utilizing the medicines (9 of 17).
As well as, the COVID-19 hospitalization price for individuals with inflammatory arthritis (26%) was much like that of New York Metropolis residents total (25%).
One other discovering was that sufferers taking biologic medicine for arthritis, comparable to adalimumab (Humira) and etanercept (Enbrel), or the antiviral hydroxychloroquine, had no larger or decrease threat of COVID-19 hospitalization than these not taking the medicine.
However sufferers who took steroids known as glucocorticoids, even in delicate doses, had a ten instances larger threat of COVID-19 hospitalization than those that did not take steroids. Though the discovering is statistically vital, the examine’s small dimension might overestimate the precise threat, the researchers famous.
The research had been not too long ago printed on-line within the journal Arthritis and Rheumatology.